№ 4, 2025

№ 4, 2025

Title page

Contents

MEDICINE

Nadiya GORCHAKOVA, Tatyana HARNYK, Igor BELENICHEV, Valeriia HNATIUK, Olena SHUMEІKO, Olena KLYMENKO, Ella GOROVA, Kateryna ROMANOVA
Signaling pathways in the mechanisms of drug action

Volodymyr BENEDIKT, Larysa KOROBKO, Pavlina NEVHADOVSKA, Roman SKOREIKO, Dmytro FYLYPIUK, Vira CHORNOUS
Determination of non-specific resistance of the organism in patients with acute intestinal obstruction

Larysa BONDARENKO, Nadiya GORCHAKOVA, Olena HOLEMBIOVSKA, Olena BESPALOVA
Epimedium Sagittatum: potential for use in sexual dysfunctions in men (literature review)

Ruslan AMINOV, Alina AMINOVA, Lyudmyla MAKYEYEVA, Oleksandr FROLOV, Yevgeny FEDOTOV, Olena POTOTSKA
Morphofunctional characteristics of incised skin wounds in rats after pharmacological correction with a water-salt extract of the medicinal leech Hirudo verbena

Yevheniia YEVTUSHENKO
The role of psychological and social factors in the development of atopic dermatitis in children

PHІSICAL THERAPY. ERGOTHERAPY

Yurii VYKHLIAIEV, Anna BEZANTS, Yuliia ANTONOVA-RAFI, Vladyslav SHLYKOV
Features of patent protection and classification of intellectual property objects in the development of innovative rehabilitation technologies for patients with prosthetics: a review of current approaches and practices

Оlena BURKA, Аlla KOVALEVA, Nataliia KORZH
Analysis of the functional training impact on musculoskeletal system condition of the of patients with the consequences of spinal compression fractures

Yurii VYKHLIAIEV, Vladyslav SLOBODIAN
Personalised approach to conservative treatment of flat feet in adults (literature review)

BIOLOGY. PHARMACY

Svitlana KAIDASH, Kateryna SOKOLOVA, Vladliena SLIESARCHUK, Tetiana POTAPOVA
Modern approaches to pharmaceutical care for аcute cough of various origins: theoretical aspects and practical recommendations for pharmacist (literature review)

Оksana MIALIUK, Oksana OKSENIUK, Volodymyr BONDAR, Mariya MARUSHCHAK, Liudmyla HERASYMENKO, Pavlina NEVHADOVSKA
The impact of optimism on the quality of life in patients with COPD

Nataliia HUDZ, Oksana RYBAK, Olga YAKYMIV, Oleksandr KRAVCHENKO, Volodymyr KOBYLIANSKYI, Tetiana ARHATENKO, Oksana NECHYPOR, Svitlana POTAPENKO
Risk analysis for public health due to non-compliance with the requirements of State Sanitary Norms and Rules (SSRN) 2.2.4-171-10 “Hygienic requirements for drinking water intended for human consumption”

Volodymyr KRASOVSKYI, Volodymyr MEZHENSKYJ, Liudmyla MEZHENSKA, Taisiia CHERNIAK, Svitlana HAPON, Svitlana POTOTSKA, Tetyana SHKURA
Morphometric analysis of Ziziphus jujuba Mill. Fruits from the Khorol Botanical Garden collection

Oksana LASLO, Lyubov MARINICH, Kateryna PANCHENKO, Mykola MARENYCH, Оleksandr LEN, Oksana DYCHENKO
Dynamics of changes in morphometric indicators and growth of vegetative mass of Malva sylvestris L. depending on the sowing scheme

Luidmula KUCHERENKO, Igor BELENICHEV, Vladyslav SLOBODIANYK, Oleksii BIHDAN, Olga KHROMYLОVA, Hanna NIMENKO
Evaluation of the nootropic and stress-protective activity of a new combined drug based on dimethylaminoethanol and sodium succinate

Sergii SHTRYGOL’, Mykyta HUTORKA, Oleksandr MEKLENBURTSEV, Dmitro KYRYLOV, Yuliya LARYANOVSKA, Halуna SLIPCHENKO, Olena RUBAN
The effect of cream with glucosamine hydrochloride and miramistin on the healing of full-thickness flat wounds in rats

Ra’no ABDULLAEVA, Nodira FARMANOVA, Viktoriia KYSLYCHENKO, Olena IOSYPENKO
The study of acute, subacute toxicity and cumulative properties of Bidens Frondosa L., harvested in Uzbekistan

Igor BENZEL
White dead nettle (Lamium Album L.) – current state of phytochemical composition and pharmacological activity research (literature review)

Olena WELCHINSKA, Iryna NIZHENKOVSKA, Ruslan MELESHKO
Implementation of the HPLC method in the pharmaceutical analysis of isoquinoline alkaloid

Liudmyla SLOBODIANIUK, Svitlana MARCHYSHYN, Svitlana DANYLIV, Larysa KRAVCHUK, Olha SLOBODIANIUK
Analysis of the fatty acids composition of Gerbera hybrid

Volodymyr HRUDKO, Halyna MELNYK, Olesia PEREPELYTSIA, Mykhaylo BRATENKO, Vladyslav CHAYUN
Identification and quantitative determination of carotenoids in the wound-healing ointment with sea buckthorn oil

Askar NYSANKULOV, Zhanerke SEITOVA, Arailym DAULBAYEVA, Murat ASHIROV, Nurgali RAKHYMBAYEV, Kairat ZHAKIPBEKOV
Introduction of modern resource-saving technologies at pharmaceutical enterprises (lean manufacturing approaches)

Liliia BUDNІAK, Olena HLUSHCHENKO, Ivanna HUMENNA, Tatiana DIADIUN, Roman KOTSYUBA, Liliіa KOSTYSHYN
Obtaining phytosubstances from Zinnia еlegans Jacq. herb and determination of their flavonoid content

Iryna TULUB, Nadiia BURDA
Study of the mineral composition of Zinnia Elegans Jacq. Raw materials

Nataliia HUDZ, Oksana RYBAK, Olga YAKYMIV, Anna FILIPSKA, Nataliіa SHAPOVALOVA, Oleksij KORYTNIUK, Raisa KORYTNIUK
Scientific and experimental justification of the composition and pharmacy technology of capsules with valerian root powder

Oleksandr DOBROVOLNYI, Lena DAVTIAN
Determination of process parameters of flavonoids extraction from bogbean (Menyanthes Trifoliata L.) using approaches of Quality by Design

Olena KONOVALOVA, Olha SHCHERBAKOVA, Bohdana YASHCHUK, Mariia KALISTA, Kateryna NOVOSAD, Valerij NOVOSAD, Vitalii MAKOVSKYI
Microscopic and histochemical study on the petiolar anatomy of species of the genus parthenocissus planch

Olha HALTSEVA, Oleksandr MASLOV, Mykola KOMISARENKO, Sergii KOLISNYK, Lyudmyla DERYMEDVID, Tetiana YUDKEVYCH,  Iryna LEBEDINETS, Olha NABOKA
Investigation of the anti-inflammatory and antioxidant activity of anhydrous gel “Hypericum-Derm”